Gastroenterology Consultants of San Antonio - Pancreatic Cancer Screening Service
Gastroenterology Consultants of San Antonio - Pancreatic Cancer Screening Service

Pancreatic Cancer Screening Service Join The Fight Against Pancreatic Cancer Prevention & Early Detection


GCSA is proud to introduce our pancreatic cancer screening program

South Texas Pancreatic Cancer Screening Service

Pancreatic adenocarcinoma (PAC) remains the 3rd leading cause of cancer death in the U.S. with an estimated 62,200 Americans diagnosed, and 49,800 succumbing to this disease in 2022. The five-year survival of stage I disease is 42%, but unfortunately only 13% of patients present this early.1 It is estimated that 10% of PAC develops as a result of a familial or an identifiable genetic predisposition. Request an Appointment Today!

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South Texas Pancreatic Cancer Screening Test Service

While screening for PC in the general population is not cost-effective, targeting high-risk populations may result in a higher likelihood of detecting precursor lesions (e.g. cystic neoplasms) or early, stage I disease with higher rates of operability and improved outcomes. The relative risk (RR) of developing PC is markedly elevated in several patient populations.

Who should be considered for screening:2

If you have a parent, sibling, or child that has been diagnosed with pancreatic cancer AND at least one other family member with pancreatic cancer, it is recommended you get screened.  If your family history or genetic testing indicates any of the following, you should visit with your doctor about the pancreatic cancer test.

  • Familial breast and ovarian syndrome: BRCA1, BRCA2, PALB2 (RR 2-22)
  • Peutz-Jeghers Syndrome: STK 11 / LKBI (RR132)
  • Hereditary pancreatitis: PRSS1, SPINK1 (RR 50-82)
  • FAMMM syndrome: CDKN2a-P16 mutation (RR 46)
  • Lynch syndrome: MLH1, MSH2, MSH6, PMS2, EPCAM (RR9)
  • Ataxia-telangiectasia: ATM mutation (RR 2.7)
  • First degree relatives (FDRs) from a familial PC kindred with at least 2 affected family members, one of which is a FDR (RR 9-32)

How are patients screened?

Screening should begin at age 40, or 10 years prior to the age of the youngest affected first-degree relative.  Two imaging tests should be completed every other year:

  • Endoscopic ultrasound, by highly experienced endosonographers, alternating annually with a contrast enhanced MRI beginning at age 50 (STK 11, age 35) or 10y prior to age of youngest affected FDR, whichever is sooner. Interval adjusted based on abnormalities. MRI ineligible patients undergo annual EUS.

Patients who are unable to undergo an MRI may undergo an EUS every year instead.  Based on any abnormalities, your doctor may recommend a different interval for these tests.

In addition to these imaging tests, doctors also recommend

  • Annual serum IMMray PanCan-d or CA 19-9
  • Genetic counseling

Who is not a candidate for routine screening?

Average risk individuals without a genetic predisposition or family history of pancreatic cancer, or only one affected family member with pancreatic cancer without an identified gene mutation.

1) American Cancer Society. Cancer Facts and Figures 2018.
2) T Keihanian et al, Gastroenterology and Hepatology June 2021.

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Pancreatic Cancer Screening

“I am so grateful for my experience with Dr. Pruitt. Dr.Pruitt did a scope of my pancreas and he was able to diagnose a mass growing in my pancreas surrounding an artery. He diagnosed my pancreatic cancer very expediently which has enabled me to begin getting treatment quickly. Dr. Pruitt was extremely compassionate, being the first doctor that has taken notice of and addressed my pain and made every effort to make me as comfortable as possible. In the procedure room, I felt as though the team was treating me as though I were a family member. They were not only courteous but also treated me with gentleness, dignity, and respect. The staff has been extremely thorough and timely with support and follow-up post-procedure. I am so thankful that God led me to Dr.Pruitt.”- Cheryl


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